Our History
THE CARIBBEAN EPIDEMIOLOGY CENTRE (CAREC)
Formerly: The Trinidad Regional Virus Laboratory
and The Colonial Microbiological Research Institute
The Caribbean Epidemiology Centre began operating on 1 January 1975 under the
administrative management of the Pan American Health Organization (PAHO) at the request of
the Caribbean Health Ministers' Conference held in the Bahamas in 1974.
Background
During 1971 and 1972 the Caribbean island of Trinidad experienced major poliomyelitis
and typhoid fever epidemics. In addition, cholera reached Portugal around that time.
Because of these developments, the territories and English-speaking countries of the
Caribbean were especially conscious of communicable disease problems not only the direct
threat posed to their inhabitants but also the potential threat to tourism, their major
industry. It was realized, however, that little accurate information existed on
communicable disease patterns in the Caribbean countries and territories. The consequent
need for good epidemiologic surveillance and backup laboratories was first stated by Dr.
Eric Williams, Prime Minister of Trinidad and Tobago, and his call for action was endorsed
by the Caribbean Health Ministers' Conference held at Dominica in 1975. In this same vein,
Dr. Williams had approached PAHO the previous year to see if the Organization would be
interested in setting up a disease surveillance center based in Trinidad that would
incorporate the activities of the existing Trinidad Regional Virus Laboratory. This
laboratory, situated near the center of Port of Spain, was used by the Rockefeller
Foundation for Arbovirus studies from 1962 to 1968, during which time it was attached to
the Department of Microbiology of the University of the West Indies. In 1968 the
Rockefeller Foundation withdrew its funding, but the University kept it in operation with
contributions from the Governments of Barbados, Guyana, Jamaica, Trinidad and Tobago,
Britain, and serial grants from the Medical Research Council of the United Kingdom and the
National Institutes of Health (USA). In response to Dr. Williams' request, PAHO sent a
team of leading scientists to examine surveillance requirements in the area. This team
presented a report in 1975 confirming the need for a disease surveillance center.
Subsequently, a Pan-Caribbean conference held in Jamaica in April 1974 endorsed plans for
performing disease surveillance work based at the Trinidad Regional Virus Laboratory. As a
result, PAHO and the Government of Trinidad and Tobago signed a bilateral agreement making
over the lands and facilities of the Trinidad Regional Virus Laboratory to PAHO for 10
years; and in October 1974 PAHO signed an additional multilateral agreement with the
Governments of the Commonwealth Caribbean. Together, these agreements provided the
structure of what was to become the Caribbean Epidemiology Centre (CAREC). By geographic
coincidence the Trinidad Public Health Laboratory was situated in the same building as
CAREC, facilitating the arrangement whereby the Director of that laboratory also became
the Assistant Director of CAREC. Very strong and essential links were thus created between
the Trinidad Public Health Laboratory and CAREC links, which have continued to develop.
The close relationship established between CAREC and the West Indies Government (through
their health Ministries and the Caribbean Health Ministers' Conference) is particularly
important.
In accord with the multilateral agreement, CAREC was established for a 10-year period
beginning on 1 January 1975. The Governments signatory to the agreement also consented to
make quota contributions providing approximately 60 per cent of CAREC's core budget, the
remaining 40 per cent to come from PAHO/ WHO, and the Overseas Development Ministry of the
U.K.
THE TRINIDAD REGIONAL VIRUS LABORATORY

The Trinidad Regional Virus Laboratory (TRVL) was established by the Rockefeller
Foundation in 1953 in a wooden building (formerly an army barracks) near the docks in
Port-of-Spain. In 1961, the Laboratory was transferred to modern buildings in Federation
Park, Port-of-Spain, some of which housed formerly the Colonial Microbiological Research
Institute. In the same year, the Laboratory became part of the Department of Microbiology
of the University of the West Indies. The research programme was concerned initially with
the study of the ecology and epidemiology of arboviruses (mosquito, mite and tick
transmitted viruses) in the Caribbean and that part of the mainland of South America which
is adjacent to the island of Trinidad. The programme of the Laboratory was also widened to
include investigations on all viruses affecting man and domestic animals in the region,
and some agents other than viruses, which are of medical importance to the region. Apart
from research, the laboratory undertook routine diagnostic work on virus diseases.

A field station was maintained by the Laboratory in Bush Bush Forest in the Nariva
Swamp. At this station, studies were carried out continuously on the arboviruses of
Trinidad. At various times, similar studies were conducted in other parts of the island.
In 1967, field activities were concentrated at Turure Forest near Sangre Grande. Many
viruses were recovered from this area.
The laboratory also provided training to research workers and technicians who came from
different parts of the world on Rockefeller Foundation or World Health Organization
fellowships.
COLONIAL MICROBIOLOGICAL RESEARCH INSTITUTE
In 1945 Sir Robert Robinson and Professor J.L. Simonsen, acting on behalf of the
Colonial Products Research Council, paid a visit to the West Indies to acquaint themselves
with the tasks in which scientific research could assist these and other tropical
territories of the Commonwealth. From the observations they made in the Colonies which
they visited, they concluded that almost every branch of science could be called upon to
take a share in raising the prosperity of these lands; but that a special claim could be
made for microbiology of which only the most urgent medical aspects had been receiving
attention in the past.
The Colonial Office accepted their conclusions and made funds available for the
foundation of a Colonial Microbiological Research Centre to be situated within the
tropics.
Port of Spain, Trinidad, was decided on as a suitable location. It was approved that
the Centre should devote its energies to fundamental research in microbiology; to the
application of the results of its investigations; and to assisting agricultural and other
industries in improving their products. Further, it was approved that the new Institute
should form a Centre for post-graduate training in microbiology. Afterwards, it was
decided that a branch of the new Centre should devote itself to the maintenance of a
collection of micro-organisms, which could be made freely available to interested
institutes and to research workers in tropical and temperate climates.
To meet the needs of the new Centre a building was designed, which, in addition to a
library, comprised six laboratories, three for microbiological and one for biochemical
research. One laboratory was reserved for the type culture collection, and one for the
preparation of culture media.
The construction of the various buildings commenced early in 1947 and by July had
progressed so far that the Institute could be opened officially on July 5, when Lord
Hankey, Chairman of the Colonial Products Research Council, consented to perform the
ceremony in person.
(Extracted from : Bull. Pan Am. Health Organ. 13 (2), 1979: 187-94)