Caribbean Epidemiology Centre

 

1998 Annual Report
Director’s Report

Introduction

Nineteen ninety-eight was the twenty-fourth year of operation of the Caribbean Epidemiology Centre (CAREC), and the third year of a transformation exercise, the goals of which are to improve the Centre’s relevance and services to member countries, to strengthen financial health, and to improve the human systems and competencies at the Centre. Major lines of action in 1998 were organised by categories of Technical Cooperation, consistent with the strategic and programmatic orientations of the Pan American Health Organization (PAHO), for the period 1995-1998; the Caribbean Cooperation in Health Initiative (CCH); CAREC’s multilateral agreement and its 1998-1999 biennial plan, together with guidance from its Council and Scientific Advisory Committee.

In the past year, the health situation has become more complex, both in terms of the emergence of new health problems, diseases and risks, and the hurricane of change in the health sector, consequent upon health sector reforms, the latter posing both a threat and opportunity for public health.

New mortality analyses, 1980-1995, show that since 1990, after decades of decline, mortality rates from communicable disease have been on the rise, with AIDS now being the major cause of death in males and females aged 15-44 yr. On the other hand, mortality from diabetes, violence and injuries also increased markedly over the same period. Emerging/re-emerging disease (EID) problems have also increased, with significant human and economic impact, particularly given the tourism dependent nature of Caribbean economies, e.g., dengue and dengue haemorrhagic fever, malaria, tuberculosis (TB), and food and water borne diseases.

Economically, the Caribbean's dependence on tourism continued to grow, while health and disease problems in some destinations caused large revenue losses. Our host Country, Trinidad and Tobago, struggled with a major fall in the price of oil. The Eastern Caribbean faced a major threat to their banana industry, with the ongoing World Trade Organisation (WTO) negotiations, and will likely have to transition their economies to tourism and other areas of activity. There was continued degradation of the physical environment, with growing concern over global climate trends, while two very damaging hurricanes and an ongoing volcanic eruption reminded all of the turbulent nature of the Caribbean.

 A more inclusive CCH phase 2 (CCH-2) has begun, recognising the primacy of the health promotion approach. Under CCH-2, the Centre has particular responsibility for disease prevention and control, and the building of epidemiologic capacity and surveillance systems responsive to the health situation.

The new CARICOM Council on Human and Social Development (COHSOD) had its first meeting in April in Jamaica, within a broader environment that is rapidly evolving technologically, financially, and politically. Following presentations on the health status of the Caribbean by CAREC/PAHO/CFNI/UNAIDS, the COHSOD resolved, inter alia, to eliminate rubella and Congenital Rubella Syndrome; to an expanded intersectoral response to HIV/AIDS/STD; to reverse the upward trend in TB; and to a campaign on diet and health. Since then, new evidence has emerged on the use of anti-retrovirals to prevent mother to child (MTCT) HIV transmission.

Technical cooperation

The body of the annual report describes the impact of the work of CAREC’s Divisions and Programmes in service, training, and research. Some of the highlights and innovations are summarized below by focus of technical cooperation and the implications for countries and the Centre discussed.

Major achievements

Major achievements include the resolutions of the COHSOD; development of goals and indicators for disease prevention and control; maintenance of the region’s polio- and measles-free status; successful in-country investigation of five outbreaks; mobilisation of new financial partners to help address important problems; improving country access to CAREC databases and the Internet through training and equipment; improved use of laboratory information in surveillance and decreased turnaround time for results through fuller implementation of the CARISURV-LABIS system; implementation of new surveillance systems - injury surveillance in the Bahamas, and the start of a laboratory surveillance network; the successful pilot of a distance education program in laboratory Quality Assurance; and much greater involvement of marginalised groups, e.g., sex workers, Men who have sex with men (MSM), People Living with AIDS (PLHA), in the fight against HIV/AIDS.

Major challenges during the year included the limitations of the aging physical plant and accommodation, the pressure on the core budget, vacancies in certain key posts, and managing the high level of donor agency interest and projects.

Resource Mobilisation

In an effort to achieve the mission of the Centre, the mobilisation of new financial, human, and information resources, and the formation of partnerships was vigorously pursued. Quota collections in the amount of $US1.57 million were received from 19 countries. This continues the trend of the previous two years of strong support from member countries, which has helped to attract a high level of donor and external agency interest in the Centre. Although member countries have paid their quotas well over the last three years, there had been no increase in the quota budgets since 1995. However, in September, the Caucus of Health Ministers, following a presentation on the work of the Centre by the Director, CAREC, approved a 3% increase in the quota budgets, pending the outcome of the review of regional health institutions, which it is hoped will begin in 1999. This modest increase in the quota budget is most welcome, as this is the main source of funding of the core work of outbreak investigations and reference services provided to CMCs.

Extra-budgetary funding amounted to 35% of the operational budget, through a total of ten grants and agreements. Grants were signed in June and October with the World Bank, Info-Dev Division, and the UK Dept. for International Development (DFID), respectively. The former (2 yr., $250,000) will support the establishment of a computerized physician sentinel surveillance system, initially in Jamaica, St Lucia and Trinidad and Tobago, in partnership with the Caribbean College of Family Physicians (CCFP). The latter will support a project on the prevention and control of HIV/STD in CARICOM countries. A complementary HIV/STD proposal for the UK dependent territories was also developed and submitted to DFID. CAREC also provided significant input into the design of regional project on HIV/AIDS prevention to be funded by the European Union, which, is intended to increase, from one to six, the range of Caribbean organisations involved in the effort.

In March, the CARIFORUM Ministers, meeting in Port of Spain, approved our project on Strengthening of Medical Laboratories in the Caribbean for $ECU 8.5 million of funding, and negotiations to finalise this are continuing. In October, the Multilateral Investment Fund of the Inter American Devlopment Bank approved $US1.3 million towards a "Caribbean Tourism, Health, Safety and Resource Conservation Project" to be implemented jointly by CAREC and the Caribbean Action on Sustainable Tourism (CAST), a subsidiary of the Caribbean Hotel Association. Detailed contractual negotiations with CAST are nearly completed. These two developments are the fruit of much effort in advocacy and negotiation, thus adding further value to the membership of the Centre. The support from these new grants will complement the support of our existing financial and technical partners as shown in our stakeholders chart.

Direct Technical Cooperation

Support was provided in-country by staff of the Centre in the management of five outbreak situations with consequent addition of valuable new information pertinent to successful disease prevention and control. These were: a cluster of autochtonous malaria in Bahamas; an outbreak of TB in Turks and Caicos Islands, a large outbreak of viral gastroenteritis due to a sewage contaminated water supply at a major hotel in Bermuda; an outbreak of Dengue and DHF in Trinidad; and an outbreak of nosocomial septicemia in Dominica. In addition, epidemiologic advice and laboratory support was rendered in eight other outbreaks. Help was also provided to St Kittsand Nevis after Hurricane Georges, and to Belize, after Hurricane Mitch, as part of the PAHO Disaster Response team.

Of note during the year was the increased capability for tracking of laboratory data and quality parameters and enhanced surveillance through improvements in the Laboratory Information System (LABIS) and in improved methods of alerting individuals inside and outside of CAREC about potential outbreaks. Improved teamwork between laboratory and epidemiology also resulted from starting a laboratory surveillance network, using the CDC Public Health Information System (PHLIS), with support from the Walter Reed Army Institute of Research.

National TB programmes in seven countries were reviewed and advocacy for improved efforts conducted. Though subject to a COHSOD resolution, progress in this area has been hindered by seeming lack of real commitment in many CMCs and lack of resources, in spite of several attempts to source extra-budgetary funds.

Dissemination of Technical Information

During the year, the communicable disease feedback report and fax alerts were used to give member countries surveillance feedback and keep them apprised of emerging disease problems. In the vector control area, community based efforts and competitions were used to sensitise on dengue prevention and environmental management. Many of the new projects will increase the range and quality of surveillance information available to countries, such as the Physician Sentinel project and the PHLIS project.

The Centre’s information and communication infrastructure was further enhanced to facilitate dissemination of information to member countries, e.g., remote access to the LAN, full time connection to the Internet and email available to all staff, and further developments are planned for 1999.

The SPSTD programme made great use of print, radio and television to inform and educate the populations of the Caribbean on HIV/AIDS prevention. Many of these campaigns were broadcast live, in collaboration with partners in Ministries of Health and in national and regional media houses. Also in this area, groundbreaking work continued with the piloting of HIV/STD prevention interventions with non-Governmental and community based organisations. These included youth, men who have sex with men, and commercial sex workers in six countries. Given the nature of HIV/STD, and the stigma and illegality surrounding some groups, working with NGOs may be only way to realise effective prevention efforts.

Development of Plans and Policies

Healthier public policy was pursued, for example, through advocacy sessions with four Governments on the human and economic impact of the HIV/AIDS epidemic and on the need for an expanded response. This has borne tangible fruit in increased resources being allocated in some countries to the HIV/AIDS programme, as well as intangible benefits, such as an enhanced profile for health, and an appreciation of the role of health in development. This approach could usefully be expanded to other key public health problems, such as traffic injury and seatbelt legislation.

Five countries were assisted to develop new national plans for HIV/STD prevention and 21 country immunisation programmes also benefited from assistance with the development of annual plans.

A significant development occurred in October when a regional workshop agreed an interim policy on prevention of maternal to child transmission (MTCT) of HIV through the use of anti-retroviral therapy in pregnancy and countries will be assisted in 1999 to develop plans and mobilise resources. This is likely to have a significant impact when fully rolled out, saving 200-400 lives per year, and avoiding much unecessary health care costs. It is also an important step in a new thrust of prevention through better care and support for people with HIV/AIDS.

Planning also began on a chronic disease surveillance system in collaboration with the CPC office and the CDC.

Training

Training and human resource development continued as part of the Centre’s core mission. Five countries had skills upgraded in the use of the Epi Info software and outbreak investigation methodology was taught in 3 countries. Teaching of epidemiology and statistics was conducted as part of the Kellogg-funded health informatics program at the Barbados Community College in collaboration with the CPC office.

In order to strengthen public health capacity in the region, a plan was developed for a pilot Field Epidemiology Training Programme (FETP). This is intended to develop cadre of public health specialists who are skilled in the application of a range of public health disciplines to contemporary health problems, and who can help provide more public health leadership in the health sector reform process. Seed resources worth $200,000 have been agreed with CDC and LCDC to start the programme, while more substantial funds are being sought. The Caribbean programme will be linked to the established FETPs of CDC and LCDC. A 2-3 year foundation period is envisaged during which potential supervisors will be identified and trained, and the academic modules (five courses) developed, in collaboration with UWI and others.

A distance education project was piloted in nine CMCs in collaboration with CDC. The first module, in laboratory quality assurance, made use of five videos developed through a cost effective alliance with the local television industry, and also using the UWIDITE system. This will be evaluated in early 1999 and will inform the CAREC master plan for distance learning.

Regional capacity in vector identification and control was enhanced through a series of courses at CAREC and in country.

Applied Research

Providing information to guide public health is a main goal of this component, through studies on health needs, disease risk factors, and on the effectiveness of interventions.

HTLV-1 research continued in collaboration with the Medical Research Foundation, e.g., a natural history and pathogenesis study of Adult T-Cell Leukemia, which has reached the halfway in subject recruitment. Notable HIV-related research was the completion of a descriptive study of men who have sex with men in six countries, which showed a high prevalence of unprotected sex, and provides the basis of planning a peer education health promotion intervention.

A descriptive and case control study of the epidemiology of S. enteritidis was commenced in collaboration with UWI and CDC in Trinidad and Tobago, Barbados, and Jamaica. Initial results from Trinidad & Tobago point to raw or partially cooked eggs being the source on infection.

A study of the prevalence and determinants of seatbelt use among 2,000 plus drivers in Trinidad and Tobago was conducted in collaboration with UWI Department of Community Health using methodology that can be replicated elsewhere. Only 42% of drivers and 30% of front seat passengers were wearing seatbelts, indicating much scope for preventing death and injuries, and avoiding health care costs through enforcement and promotion of the law. Results were publicised via the media in Trinidad and Tobago over the Christmas period.

In the vector control area, baseline filariasis studies were completed in two countries, which provides a potential model for certification of elimination in other countries. Chagas disease prevalence was measured in three countries. A case control study of DHF was done in Trinidad and Tobago, which showed that significant environmental management changes only occurred in homes where someone had died of DHF. Limited effectiveness of dynafoggers in controlling Aedes was demonstrated in Trinidad and Tobago, pointing out yet again the need for greater community involvement in control efforts.

Antimicrobial resistance of enteric pathogens is being studied in six countries in collaboration with LCDC and PAHO, providing information to help guide treatment. The gonococcal anti-microbial susceptibility study continued. Dengue PCR was shown to compare favourably to viral isolation, and has the advantage of speed in the identification of serotypes.

Management of the Centre

The Centre continued the transformation began in 1996, with the goals of improving relevance and service to member countries, improving financial health, and developing a staff more competent in the technical and people skills necessary for effective function in today's environment.

In terms of the first goal, the range of services and surveillance systems provided through the Centre is now more relevant to the current health situation in member countries. Most of the results set in projects were achieved, although a tendency was noted for the overestimation of what is achievable in a given time. Outbreak management assistance was particularly valued, and directly related to the approval of the 3% increase in the quota budgets by Ministers.

Given the health situation, the main gaps include chronic disease and behavioural risk factor surveillance to inform health promotion campaigns. Planning for these is underway. Second, given the range and amount of surveillance, evaluation and applied research information that is generated by the Centre's programmes, there is much room for improvement of service to CMCs through more regular and effective feedback to a variety of publics. There is also much scope for helping countries increase the use of available information. Third, although much training is conducted, there is a need for a plan and program of training to build capacity, particularly in applied epidemiology.

Physical plant issues adversely affected activities during the year. A major difficulty occurred when staff in the Epidemiology building had to be relocated off-campus for six months to permit renovation of the roof, rewiring, and asbestos removal. This included staff from Epidemiology, Statistics, Human resource, Healthy Hotels, and the Public Health Intelligence unit. A continuing concern during the year was our inability to pursue renovations to create an appropriate facility for surveillance of emerging viruses, including animal innoculation, due to lack of budgetary allocation for such, and the failure to date of several efforts to access extra-budgetary support for this purpose.

In December we experienced a major problem with leaking over the main block of the Centre, which houses much of administration and some laboratories, following an attempt to repair the roof. This problem is not yet resolved and many functions have had to be relocated to the training laboratory and lecture theatre, while the funding and support is sought for the construction of a roof over the main block. Staff are to be commended for their tolerance and flexibility in coping with this situation, which has slowed down the issuing of some test results.

These situations highlighted the overall issue of the shortage of accommodation for all the projects coming on stream, as well as the main plant being over 60 years old. In 1999, it is intended to update and re-cost the master plan, prepared in 1992, and to begin a capital drive.

With respect to the financial situation, the quota budget continued to perform well, with 19/21 countries having paid 93% of the assessed quotas as detailed in the Administration Manager’s report. The PAHO regular funds continued with no increase, although a successful over the ceiling request for building works augmented the budgeted amount. Two new grants worth $1.5 million were signed and several others are in the pipeline.

The staff at the Centre continued to give of their best in a situation where the demands exceed available resources. The Human Resource Department also increased the range and quality of services provided thus improving organisational effectiveness. Staffing at the Centre was at near full complement, but key vacancies existed that hindered technical cooperation. Among the PAHO staff, the Epidemiologist acted and was then confirmed as Director, CAREC in August. The Virologist post was vacant from the end of June and this impacted negatively on the progress of virology and molecular biology. Towards the end of the year, part time assistance was arranged with the previous virologist (now retired) to provide some support while the position is being filled.

Among the CAREC staff, vacancies in the virology, information technology, and materials management were not filled, indicating the shortage of these skills in this market as well as the competitive nature of the Information Technology market. In this regard, CAREC staff benefits are still not on par with the agreed comparator, CARICOM, and this needs to be addressed if we are to be more competitive in attracting and retaining good staff. Much needed progress was made in strengthening the Epidemiology Division, with the hiring of an epidemiologist who will focus on laboratory surveillance, and the assignment of an Epidemiologist from the French Technical Cooperation in June and December, respectively.

Complete implementation of new multi-source feedback staff appraisal system was a noteworthy achievement and has informed the staff development plan. There was a small positive increase in average scores in most areas measured between the probationary period and the second annual appraisal.

Perspectives and Recommendations

The level of outbreak and emergency support required of the Centre by member countries during the year continued the trend of the previous year, and was markedly different from earlier years, indicating that changes have occurred in the factors influencing the occurrence and recognition of outbreaks. The need to meet these demands through increased staff travel and the purchase of reagents, etc., reduced the allocated amounts for necessary equipment and infrastructure improvements.

The factors linked to the EID situation include ever-increasing travel; emergence/re-emergence of pathogens, e.g., Dengue virus type 3 and DHF, TB, S. enteritidis PT4, brucella, anti-microbial resistant strains, and weakening of the public health infrastructure. At the same time, the increase in mortality from diabetes and injuries indicates further changes in the underlying risk factors and behaviours favouring the emergence of non-communicable disease, and the challenge of increasing in-equity and poverty in many countries, which together with the drug trade, for example, fuel conflict.

These situations emphasize the need to strengthen national public health capacity and the science base for public health, particularly in applied epidemiology, disease surveillance and response, as outbreaks can have a disproportionate economic impact, given the tourism-dependent nature of many of our economies. In this regard, a new Caribbean communicable disease surveillance manual has been prepared with assistance from Emory School of Public Health and will be used for training in the future. Secondly, the establishment of the FETP will be vigorously pursued.

In responding to the health challenges, the CCH-2 initiative has agreed to use the health promotion approach, though exactly how this will be applied to the eight agreed priorities needs further elaboration. It will likely include more use of advocacy at national and regional levels to influence healthy public policy, based public health surveillance information; leveraging the health sector reform process to benefit public health; supporting healthy behaviour change through information, education and communication; and the building of alliances with non-traditional partners. It is clear that the Centre, while maintaining its core purpose of improving the health of Caribbean people, has been evolving its strategy to a more explicit health promotion approach, in order to support member countries in responding to the health situation. This will continue in 1999 and beyond.

Under CCH-2, information to bring about change and to track progress towards objectives will be key. Recognising the pivotal role of the use of information and Information Technology in health promotion and disease prevention, greater emphasis was placed on capacity development in this area during the year, while a multi-disciplinary ICT team under the D/CAREC was formed to develop the 2000-01 plan. More effective communication to a range of internal and external publics to improve health, prevent disease and develop alliances will be a major future emphasis.

Although the new surveillance systems being developed by the Centre will expand the range of information available to countries, there is a need to integrate surveillance systems into a more holistic model, particularly for smaller countries. In this regard, the CARISURV concept will be further developed during 1999, as an umbrella or tree with many parts or modules, which are connected. This reflects the need for a range of approaches, tools and instruments needed to measure and track health status and trends in our populations.

With regard to the financial situation, the short-term outlook is a bit healthier than in the past, particularly where grants and contracts are concerned. The performance in this area is directly linked to country support via the quotas. As detailed in my last Director’s report, the success with grants requires a tremendous effort in developing, negotiating, managing and reporting on them. A projects unit is needed be more effective as grants and contracts will continue to increase in importance. With the multiplicity of financial partners, there is also a need for improved donor coordination to achieve more synergy, and to free staff of inordinate reporting requirements. Between the various PAHO, CAREC and donor reporting requirements, the same project can be reported upon three times, which is wasteful. An important point also is that grant funding tends to be tied to specific programmes with insufficient overheads being paid to the Centre for operating expenses, essential maintenance or much needed development work. There is a need therefore to find sources of uncommitted funds that can be used for these purposes.

To manage the Centre more effectively and to position it to survive and thrive, an Institutional Strengthening Project will be undertaken with funding from the UK DFID.

The purpose is to further transform the organisation to better meet increased and changing country needs for service, and to continously respond to the changing

economic, political and technological environment. The project's expected results will increase the Centre's capacity in three inter-related areas: HR, information and communication, and improved financial management.

In closing, on a personal note, I would like to thank all those who have supported the Centre during the year, particularly the staff in Ministries of Health in member countries, staff at CAREC, staff in PAHO representations and at headquarters, and the several donor and technical agencies who are our partners.

C. James Hospedales

Director

 


Caribbean Epidemiology Centre
16-18 Jamaica Boulevard, Federation Park
P.O. Box 164, Port of Spain
Republic of Trinidad and Tobago
Tel: (868) 622-4261, Fax: (868) 622-2792
E-mail: postmaster@carec.paho.org

Page last modified 21 May, 1999