Caribbean Epidemiology Centre

 

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Surveillance guidelines in response to anthrax threats

 

Given the recent global threat of biological terrorism with anthrax, the public health infrastructure in all countries must be prepared to prevent the illnesses that may result from exposure to anthrax. Preparedness activities need to focus on:

Prevention and early detection
Response
Diagnosis
Surveillance
Communication

Detection and diagnoses of illnesses caused by biological terrorism, including exposure to anthrax, is a complex process that involves numerous partners and activities. Meeting this challenge will require special emergency preparedness at all levels. CAREC will assist in the provision of public health guidelines, providing technical assistance to all countries in the development of coordinated preparedness plans and response protocols to meet the challenge. All countries will require a comprehensive plan.

 

Early prevention and detection

Early detection of exposure and prevention of disease is essential to ensure a prompt response to an exposure to anthrax. A major element in facilitating early detection is to have a heightened awareness and index of suspicion among the general population, as well as among all health care providers. Vaccines are not recommended for the general population.

 

Response

If someone reports opening a parcel or letter with contents suspicious for anthrax (e.g. powder), the comprehensive public health response should include an epidemiological investigation, medical management and prophylaxis for affected persons (see attached guidelines for physicians). If necessary, initiation of disease prevention or environmental decontamination measures should be put in place.

There is no screening test available for the detection of anthrax infection in an asymptomatic person. In general, the use of nasal swabs to evaluate an anthrax threat is discouraged. The use of nasal swabs in recent investigations in Florida and NYC has been for epidemiological purposes only, in order to determine who was at highest risk of exposure in situations where there is a confirmed case. The results have been used to guide further investigation and to determine the source of exposure. The results cannot be used to determine preventive therapy. The sensitivity and specificity and clinical value of nasal swab testing are unknown.

The one exception, where nasal swabs may be useful, is in the situation where there is a highly credible exposure potential and there is no discrete environmental source to test. An example is that of a person who got a "blast" of powder in the face - and the powder was cleaned up before there was any police involvement and was subsequently irretrievable for laboratory testing."

 

Diagnosis

Samples of white powder suspicious for anthrax or clinical samples if indicated, should be sent to your public health laboratory for testing. Please refer to the enclosed laboratory procedures for the identification of Bacillus anthracis.

 

Surveillance

In the event of a possible exposure to anthrax, the following should be done:

Obtain a list of names and contact details of all persons who were possibly exposed to the white powder suspicious for anthrax.
Monitor these persons daily for symptoms of anthrax infection:
If the test result is negative, discontinue daily monitoring and medical management
It the test result is positive refer to the Guidelines for Physicians
If test results are unavailable and the person is asymptomatic after ten (10) days, discontinue daily monitoring

Communication

Communication must take place at all levels:

The public should be informed of whom to contact in the event of a possible anthrax exposure. Effective communication with the public through the news media will also be essential to limit public panic and disruption to daily life (see attached information sheets for the public). Additionally, the public should be reminded not to pressure physicians for antibiotics.
A hotline should be established to receive calls for information or reports of possible exposure to anthrax.
Laboratories must be provided with guidelines for the handling, transportation and testing of environmental and clinical specimens for anthrax.
Health care providers should be reminded of the clinical presentation of and treatment for anthrax (see guidelines for physicians). They must also be informed that all cases of anthrax (suspected and confirmed) should be reported and logged.
CAREC is requesting that all suspected and confirmed cases of anthrax be reported to this Centre.

 

Reference:

CDC Biological and chemical Terrorism: Strategic plan for preparedness and response. MMWR, April 21, 2000 / Vol. 49 / No. RR-4

 


Caribbean Epidemiology Centre
16-18 Jamaica Boulevard, Federation Park
P.O. Box 164, Port of Spain
Republic of Trinidad and Tobago
Tel: (868) 622-4261, Fax: (868) 622-2792
E-mail: postmaster@carec.paho.org

Page last modified 22 October, 2001